USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P47897 USC-OGP 2-DE database:  P47897 P47897 General information about the entry View entry in simple text format Entry name SYQ_HUMAN Primary accession number P47897 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Glutamine--tRNA ligase; EC=6.1.1.18; AltName: Full=Glutaminyl-tRNA synthetase; Short=GlnRS;. Gene name Name=QARS Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1258: pI=6.30; Mw=30200 Cross-references UniProtKB/Swiss-Prot P47897; SYQ_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SYQ_HUMAN Primary accession number P47897 Secondary accession number(s) B4DWJ2 Sequence was last modified on  February 1, 1996 (version 1) Annotations were last modified on  March 15, 2017 (version 171) Name and origin of the protein Description RecName: Full=Glutamine--tRNA ligase; EC=6.1.1.18; AltName: Full=Glutaminyl-tRNA synthetase; Short=GlnRS; Gene name Name=QARS Encoded on Name=QARS Keywords 3D-structure; Acetylation; Alternative splicing; Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Epilepsy; Ligase; Nucleotide-binding; Phosphoprotein; Primary microcephaly; Protein biosynthesis; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X76013; CAA53600.1; -; mRNA EMBL AK301559; BAG63054.1; -; mRNA EMBL AC135506; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC000394; AAH00394.1; -; mRNA EMBL BC001567; AAH01567.1; -; mRNA EMBL BC029739; AAH29739.1; -; mRNA CCDS CCDS2788.1; -. [P47897-1]; . CCDS CCDS63633.1; -. [P47897-2]; . PIR I37422; I37422; . RefSeq NP_001259002.1; NM_001272073.1. [P47897-2]; . RefSeq NP_005042.1; NM_005051.2. [P47897-1]; . UniGene Hs.79322; -; . PDB 4R3Z; X-ray; 4.03 A; C=1-775 PDB 4YE6; X-ray; 2.40 A; A=1-775 PDB 4YE8; X-ray; 3.30 A; A=1-775 PDB 4YE9; X-ray; 2.70 A; A=1-775 PDBsum 4R3Z; -; . PDBsum 4YE6; -; . PDBsum 4YE8; -; . PDBsum 4YE9; -; . ProteinModelPortal P47897; -; . SMR P47897; -; . BioGrid 111797; 126; . IntAct P47897; 98; . MINT MINT-5004268; -; . STRING 9606.ENSP00000307567; -; . BindingDB P47897; -; . ChEMBL CHEMBL3054; -; . DrugBank DB00130; L-Glutamine; . MoonProt P47897; -; . iPTMnet P47897; -; . PhosphoSitePlus P47897; -; . SwissPalm P47897; -; . DMDM 1351170; -; . EPD P47897; -; . MaxQB P47897; -; . PaxDb P47897; -; . PeptideAtlas P47897; -; . PRIDE P47897; -; . DNASU 5859; -; . Ensembl ENST00000306125; ENSP00000307567; ENSG00000172053. [P47897-1]; . Ensembl ENST00000414533; ENSP00000390015; ENSG00000172053. [P47897-2]; . GeneID 5859; -; . KEGG hsa:5859; -; . UCSC uc003cvx.5; human. [P47897-1]; . CTD 5859; -; . DisGeNET 5859; -; . GeneCards MIR6890; -; . GeneCards QARS; -; . HGNC HGNC:9751; QARS; . HPA HPA036986; -; . HPA HPA036987; -; . MalaCards MIR6890; -; . MalaCards QARS; -; . MIM 603727; gene; . MIM 615760; phenotype; . neXtProt NX_P47897; -; . OpenTargets ENSG00000172053; -; . Orphanet 404437; Diffuse cerebral and cerebellar atrophy-intractable seizures-progressive microcephaly syndrome; . PharmGKB PA34093; -; . eggNOG KOG1148; Eukaryota; . eggNOG COG0008; LUCA; . GeneTree ENSGT00550000074972; -; . HOGENOM HOG000259233; -; . HOVERGEN HBG000889; -; . InParanoid P47897; -; . KO K01886; -; . OMA FNAFKIL; -; . OrthoDB EOG091G026F; -; . PhylomeDB P47897; -; . TreeFam TF105683; -; . Reactome R-HSA-2408517; SeMet incorporation into proteins; . Reactome R-HSA-379716; Cytosolic tRNA aminoacylation; . Reactome R-HSA-379726; Mitochondrial tRNA aminoacylation; . ChiTaRS QARS; human; . GeneWiki QARS; -; . GenomeRNAi 5859; -; . PRO PR:P47897; -; . Proteomes UP000005640; Chromosome 3; . Bgee ENSG00000172053; -; . CleanEx HS_QARS; -; . ExpressionAtlas P47897; baseline and differential; . Genevisible P47897; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0005759; C:mitochondrial matrix; TAS:Reactome; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0004819; F:glutamine-tRNA ligase activity; TAS:Reactome; . GO GO:0007420; P:brain development; IMP:UniProtKB; . GO GO:0006425; P:glutaminyl-tRNA aminoacylation; IDA:UniProtKB; . GO GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome; . Gene3D 1.10.1160.10; -; 1; . Gene3D 2.40.240.10; -; 2; . Gene3D 3.40.50.620; -; 2; . InterPro IPR001412; aa-tRNA-synth_I_CS; . InterPro IPR004514; Gln-tRNA-synth; . InterPro IPR007638; Gln-tRNA-synth_Ib_RNA-bd_2; . InterPro IPR007639; Gln-tRNA-synth_Ib_RNA-bd_N; . InterPro IPR000924; Glu/Gln-tRNA-synth; . InterPro IPR020061; Glu/Gln-tRNA-synth_Ib_a-bdl; . InterPro IPR020058; Glu/Gln-tRNA-synth_Ib_cat-dom; . InterPro IPR020059; Glu/Gln-tRNA-synth_Ib_codon-bd; . InterPro IPR020056; Rbsml_L25/Gln-tRNA_synth_b-brl; . InterPro IPR011035; Ribosomal_L25/Gln-tRNA_synth; . InterPro IPR014729; Rossmann-like_a/b/a_fold; . Pfam PF00749; tRNA-synt_1c; 1; . Pfam PF03950; tRNA-synt_1c_C; 1; . Pfam PF04558; tRNA_synt_1c_R1; 1; . Pfam PF04557; tRNA_synt_1c_R2; 1; . PRINTS PR00987; TRNASYNTHGLU; . SUPFAM SSF50715; SSF50715; 1; . TIGRFAMs TIGR00440; glnS; 1; . PROSITE PS00178; AA_TRNA_LIGASE_I; 1; .

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